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Chapter 2: Cardiovascular
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Management of atrial fibrillation
Management of other arrhythmias
Drugs that prolong the QT interval
Anticoagulation prescribing guidance
Management of suspected deep vein thrombosis (DVT) and pulmonary embolism (PE)
Secondary prevention of stroke / TIA
Management of angina
Chronic heart failure guidance
Management of hypertension
Management of blood lipids
2.1 Positive inotropic drugs
2.2 Diuretics
2.3 Anti-arrhythmic drugs
2.4 Beta-adrenoceptor blocking drugs
2.5 Hypertension and heart failure
2.6 Nitrates, calcium-channel blockers, and other antianginal drugs
2.7 Sympathomimetics
2.8 Anticoagulants and protamine
2.9 Antiplatelet drugs
2.10 Stable angina, acute coronary syndromes, and fibrinolysis
2.11 Antifibrinolytic drugs and haemostatics
2.12 Lipid-regulating drugs
2.14 Miscellaneous cardiovascular preparations
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2.5.1 Vasodilator antihypertensive drugs
First Line
Second Line
Specialist
Hospital Only
Hydralazine
- Tablets 25mg, 50mg (£8.80 = 50mg four times a day)
- Injection 20mg (dry powder)
Indications
- Heart failure (with long-acting nitrate) when an ACE inhibitor is contra-indicated or not tolerated
Bosentan
- Tablets 62.5mg, 125mg
Indication
- Treatment of digital ulceration (DU) in systemic sclerosis in adults
Notes
- NHS England (NHSE) will commission sildenafil and bosentan for patients requiring treatment of digital ulceration in systemic sclerosis in adults, in accordance with the criteria outlined in the NHSE Commissioning Policy
- Patients requiring treatment with bosentan will be referred by their usual consultant rheumatologist for an opinion from a specialised rheumatology centre
