4.2.1 Antipsychotics drugs

Antipsychotics (first-generation)

Haloperidol
  • Capsules 500 micrograms (£1.18 = 30 capsules)
  • Tablets 1.5mg, 5mg, 10mg, 20mg (£12.95 = 10mg x 28)
  • Oral liquid 5mg/5ml (£6.47 = 100ml)
  • Injection 5mg/ml (£0.87 = ampoule)

Indications

Levomepromazine
  • Tablet 25mg (£20.26 = 84 tablets)
  • Injection 25mg/ml (£2.01 = 1ml ampoule)

Indications

Sulpiride
  • Tablets 200mg, 400mg (£18.80 = 30 x 400mg)
  • Oral solutionSF 200mg/5ml (£27.00 = 150ml)

Indications

Antipsychotics (second-generation)

Amisulpride
  • Tablets 50mg, 100mg, 200mg, 400mg (£16.43 = 400mg daily)
  • Solution 100mg/ml (£36.00 = 60ml)

Indications

Aripiprazole
  • Tablets 5mg, 10mg, 15mg, 30mg (£1.86 = 15mg daily)
  • Orodispersible tablets 10mg, 15mg (£79.57 = 15mg daily)

Indications

Notes

  1. NICE TA213 Schizophrenia - aripiprazole (January 2011)
  2. NICE TA292 Bipolar disorder (adolescents) - aripiprazole (July 2013)
Olanzapine
  • Tablets 2.5mg, 5mg, 7.5mg, 10mg, 15mg, 20mg (£1.05 = 10mg daily)
  • Orodispersible tablets 5mg, 10mg, 15mg, 20mg (£2.26 = 10mg daily)

Indications

Quetiapine
  • Tablets 25mg, 100mg, 150mg, 200mg, 300mg (£3.13 = 400mg daily)
  • Zaluron® XL tablets modified release 50mg, 150mg, 200mg, 300mg, 400mg (£43.87 = 400mg daily)

Indications

Notes:

  1. Quetiapine modified release tablets should only be used when individuals cannot tolerate immediate-release or if concordance with a twice daily regimen is difficult.
Risperidone
  • Tablets 500 micrograms, 1mg, 2mg, 3mg, 4mg (£1.47 = 2 x 3mg daily)

Indications

Notes:

  1. Due to their cost risperidone 6mg tablets have not been included in the formulary. Prescribing 2 x 3mg tablets costs significantly less.
  2. No new patients will receive risperidone long-acting injection. There is an existing cohort of patients who will continue to receive risperidone.
Clozapine
  • Tablets 25mg, 100mg
  • Suspension 50mg/ml

Indications

  • Schizophrenia in patients unresponsive to, or intolerant of, conventional antipsychotic drugs

Notes:

  1. The patient, prescriber and supplying pharmacist must be registered with the appropriate company Patient Monitoring Service. It takes several days to do this.

 

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