4.8.2 Drugs used in status epilepticus

Drugs used for Status epilepticus not listed below:




  • Oromucosal solution 5mg/ml prefilled oral syringe 2.5mg, 5mg, 7.5mg, 10mg (£22.88 = 10mg prefilled oral syringe)


  • >6 months to <1 year: 2.5mg
  • 1 year to <5 years: 5mg
  • 5 years to <10 years: 7.5mg
  • 10 years to <18 years: 10mg
  • 18 years and older: 10mg (unlicensed)


  1. Prescribe by brand (the brand of midazolam should be specified on the individual patient care plan)
  2. Buccolam® brand is recommended for new initiations
  3. Prescribers are reminded that the different brands of buccal midazolam contain different concentrations of the drug
  4. For patients currently established on Epistatus® brand (10mg/ml, non-formulary), continued prescribing is accepted, however there should be no new initiations without careful clinical consideration
  5. The brand should not be changed without the full involvement of specialist and patient/carer
  6. For infants between 3-6 months of age treatment should be in a hospital setting where monitoring is possible and resuscitation equipment is available
  7. Although the pack size is 4 prefilled oral syringes, Buccolam® may be prescribed and dispensed in singles. To prevent wastage, please prescribe only as many prefilled syringes as necessary.
  • Tablets 1mg (£4.41 = 1mg daily)



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