Neural tube defects (prevention in pregnancy)

Women at a low risk of conceiving a child with a neural tube defect should be advised to take folic acid as a medicinal or food supplement at a dose of 400 micrograms daily before conception and until week 12 of pregnancy. Women who have not been taking folic acid and who suspect they are pregnant should start at once and continue until week 12 of pregnancy.

GPs should prescribe folic acid 5mg daily to women who:

  • have a BMI of 30kg/m2 or greater, starting at least one month before conception and continuing during the first trimester of pregnancy. See full RCOG guidance on the care of women with obesity in pregnancy
  • (or their partner) have a neural tube defect
  • have had a previous baby with a neural tube defect
  • (or their partner) have a family history of neural tube defects
  • have diabetes
  • have sickle-cell anaemia
  • are taking antiepileptic medicines
Last updated: 17-06-2019

 

Home > Formulary > Chapters > 9. Blood and nutrition > Neural tube defects (prevention in pregnancy)

 

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