1.2 Antispasmodics and other drugs altering gut motility

Antimuscarinics

Hyoscine butylbromide

• Tablets 10mg (£12.00 = 20mg four times daily)

Indications

• Irritable bowel syndrome

Dose

• 20mg four times daily

Antispasmodics

Mebeverine

• Tablets 135mg (£5.90 = 135mg three times daily)

Indications

• Irritable bowel syndrome

Dose

• 135mg three times daily

Peppermint oil

• Gastro-resistant capsules 0.2ml (£7.04 - £14.08)

Indications

• Irritable bowel syndrome

Dose

• 1–2 capsules, swallowed whole with water, 3 times daily

Notes

1. Avoid peppermint oil in patients with hiatus hernia or reflux. Peppermint oil may cause rectal stinging.
2. Mintec capsules should not be taken by patients with a history of allergy to aspirin or aspirin-like products.

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