1.2 Antispasmodics and other drugs altering gut motility

Antimuscarinics

Hyoscine butylbromide
  • Tablets 10mg (£12.00 = 20mg four times daily)

Indications

Dose

  • 20mg four times daily

Antispasmodics

Mebeverine
  • Tablets 135mg (£5.90 = 135mg three times daily)

Indications

Dose

  • 135mg three times daily
Peppermint oil
  • Gastro-resistant capsules 0.2ml (£7.04 - £14.08)

Indications

Dose

  • 1–2 capsules, swallowed whole with water, 3 times daily

Notes

  1. Avoid peppermint oil in patients with hiatus hernia or reflux. Peppermint oil may cause rectal stinging.
  2. Mintec capsules should not be taken by patients with a history of allergy to aspirin or aspirin-like products

Antipropulsives

Eluxadoline
  • Tablets 75mg, 100mg

Notes

  1. NICE TA471: Eluxadoline for treating irritable bowel syndrome with diarrhoea (August 2017)

 

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