Anti-oestrogens

Clomifene

• Tablets 50mg (£9.47 = 28 tablets)

Anterior pituitary hormones

Corticotrophins

Tetracosactide

• Injection 250micrograms/ml
• Depot injection 1mg/ml

Gonadotrophins

Chorionic gonadotrophin

• Injection 1,500unit, 5,000unit

Growth hormone

Somatropin

• See BNF for preparations

Notes

1. Refer to individual shared care guidelines for use in Endocrine conditions
   
2. Prescribe by brand. A biosimilar medicine is a biological medicine that is highly similar and clinically equivalent (in terms of quality, safety, and efficacy) to an existing biological medicine however they cannot be considered generic equivalents of the originator biological medicine. Because they are not identical, biological medicines must be prescribed by brand. The decision which brand to prescribe rests with the responsible clinician in consultation with the patient. Automatic substitution of brands at the point of dispensing is not appropriate for biological medicines.
3. NICE TA64: Recombinant human growth hormone (somatropin) treatment is recommended for the treatment of adults with growth hormone (GH) deficiency only if they fulfil the criteria of the NICE TA (August 2003)
   NICE TA188: Somatropin (recombinant human growth hormone) is recommended as a treatment option for children with growth failure when used in line with the NICE TA (May 2010) (NHS England Commissioned)

Somatrogon

• Solution for injection pre-filled pens 24mg/1.2ml, 60mg/1.2ml

Notes

1. NICE TA863: Somatrogon (Ngenla) is recommended, within its marketing authorisation, as an option for treating growth disturbance cause by growth hormone deficiency in children and young people aged 3 years and over (February 2023)

Hypothalamic hormones

Gonadorelin

• Injection 100microgram