See 4.10 Drugs used in substance dependence

Thiamine (vitamin B1)

• Tablets 50mg, 100mg (£2.75 = 100 x 100mg tablets)

Indications

• Assisted alcohol withdrawal
• Maintenance treatment following alcohol withdrawal

Pyridoxine (vitamin B6)

• Tablets 10mg, 20mg, 50mg (£34.77 = 50mg three times daily)
• Injection (unlicensed)

Indications and dose

• Deficiency states
  • 20–50mg up to 3 times daily
• Isoniazid-induced neuropathy
  • Prophylaxis: 10mg daily
  • Treatment: 50mg three times daily
• Idiopathic sideroblastic anaemia

Notes

1. Pyridoxine may also given in high doses for hyperoxaluria.

Vitamin B Compound Strong

• Tablets containing nicotinamide 20mg, pyridoxine 2mg, riboflavine 2mg, thiamine 5mg (£5.70 = 2 three times a day)

Indications

• For use in patients requiring additional nutritional support, for example eating disorders, poor oral intake and patients at risk of refeeding syndrome
• Vitamin B compound strong is no longer recommended in the treatment of alcohol withdrawal

Pabrinex Intramuscular High Potency

• Solution for injection

Notes

1. For intramuscular use only
2. Each presentation (carton) contains pairs of 5 ml and 2 ml ampoules. Each pair of ampoules consists of one 5 ml and one 2 ml ampoule to be used in treatment, labelled as Pabrinex No. 1 and Pabrinex No. 2.
   
   1. Each 5ml Pabrinex No 1 ampoule contains pyridoxine hydrochloride 50mg, riboflavin 4mg, and thiamine hydrochloride 250mg
   2. Each 2ml Pabrinex No 2 ampoule contains ascorbic acid 500mg and nicotinamide 160mg

Pabrinex Intravenous High Potency

• Concentrate for solution for infusion

Notes

1. For intravenous use only
2. Each presentation (carton) contains either 5 ml or 10 ml ampoules. Each pair of ampoules to be used in treatment is labelled Pabrinex No 1 and Pabrinex No 2.
   1. Each 5ml Pabrinex No 1 ampoule contains pyridoxine hydrochloride 50mg, riboflavin 4mg, and thiamine hydrochloride 250mg
   2. Each 5ml Pabrinex No 2 ampoule contains ascorbic acid 500mg, anhydrous glucose 1g, and nicotinamide 160mg