Referral

Heavy Menstrual Bleeding Without Histological or Structural Abnormality

Key Messages

Scope

Heavy Menstrual Bleeding (HMB) without histological or structural abnormality.

    Referral for specialist advice and surgery, if appropriate, is only commissioned in women without significant fibroids or structural or histological abnormalities, if they have failed treatment with appropriate pharmacotherapy including the levonorgestrel-IUD (LNG-IUD). Heavy Menstrual Bleeding - Referral for Surgical Management - North & East

    NICE guidance from March 2018 (Overview | Heavy menstrual bleeding: assessment and management | Guidance | NICE) suggests it is reasonable to start treatment for HMB "without investigating the cause if the woman's history and/or examination suggest a low risk of fibroids, uterine cavity abnormality, histological abnormality or adenomyosis". This guidance outlines what treatment and investigation should be considered in such circumstances and when, if pharmacological treatment including IUS fails, it might be suitable to refer. Referral for specialist advice and surgery, if appropriate, is only commissioned in idiopathic HMB if certain criteria are met. See referral section.

    Out of Scope

    Patients with:

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    History

    • Menorrhagia is defined as:
      • excessive menstrual blood loss which interferes with the woman’s physical, emotional, social and material quality of life, alone or in combination with other symptoms.
    • Check risk factors for endometrial pathology (impact on threshold for investigation/referral):
    • BMI greater than 40
    • Family History/genetic predisposition (Lynch/Cowden syndrome)
    • Unopposed oestrogen
    • PCOS
    • Diabetes
    • Tamoxifen

    Please specify any risk factors in the clinical referral details as they may influence the prioritisation of the referral

    Examination

    • Pelvic and speculum examination:
      • if the history is suggestive of structural or histological abnormality (e.g. IMB, PCB or pain),
      • or a Levonorgestrel-IUD is the chosen treatment
    • Perform smear if overdue

    Please specify any risk factors in the clinical referral details as they may influence the prioritisation of the referral

    • Pelvic (transvaginal if available) ultrasound scan:
      • if structural abnormality is suspected
      • the uterus is palpable abdominally
      • or if there is failure of pharmacological treatment.
    • Full blood count (FBC)
      • recommended for all women with HMB

    • Investigations that may be considered but are generally not indicated:
      • ferritin, gonadotrophin levels, thyroid function test (only if other signs or symptoms suggest thyroid disease), coagulation studies (e.g. von Willebrand’s) only if HMB since menarche, personal or family history suggestive of coagulation disorder.

    Management

    Treatment aims are to improve quality of life and alleviate associated symptoms, not necessarily to cure heavy bleeding.

    All patients should be strongly encouraged to keep BMI in health range; obesity contributes to high circulating oestrogens and heavy menstrual bleeding. Surgical management is likely to be declined if BMI is over 35. Please see Adult weight management pathway - North & East

    Discuss treatment options taking into account the woman’s choices and preferences including the desire to retain fertility/uterus, the benefits and harms of treatment and the clinical considerations (comorbidities, multiple pathologies, size of uterus)

    The following treatment options are appropriate when:

    • there is no identified pathology
    • there are fibroids of less than around 3cm that do not distort the uterine cavity significantly
    • adenomyosis is suspected.

    Adenomyosis that is suspected on USS can be managed in primary care using any of the following options. This finding does not require a referral to secondary care.

    It is appropriate to try one option and consider an alternative after 3 cycles if unsuccessful.

    First Line

    Levonorgestrel-IUD

    • Women should persevere for at least 6 cycles to see benefit
    • Can be used in conjunction with non-hormonal treatment (and sometimes hormonal treatment – unlicensed)

    Please note that sexual health services are only able to offer LNG-IUD for contraception. They are not commissioned to provide LNG-IUD fitting for heavy menstrual bleeding alone. If fitting of LNG-IUD is not available in your surgery please send a written referral to your local gynaecology service or if the patient is under 55 and a resident of North Devon, East Devon or Torbay consider referral to non-contraceptive LARC service.

    South & West - Non contraceptive LARC fitting - LNG-IUD fits

    North & East - Non contraceptive LARC fitting - LNG-IUD fits

    Formulary chapter 7.3.2 Progestogen-only contraceptives:

    Second Line
    • NSAIDs may be 1st choice where dysmenorrhoea co-exists
    • Combined Oral contraceptive, for a minimum trial 3 months, unless UKMEC contraindicated
    • Tranexamic acid

    UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) | FSRH

    COCP: 7.3.1 Combined hormonal contraceptives (CHC) - North & East

    TXA: 2.11 Antifibrinolytic drugs and haemostatics - North & East

    NSAIDS: 10.1.1 Non-steroidal anti-inflammatory drugs (NSAIDs) - North & East

    Third Line
    • Progesterones

    Progestogens: 6.4.1 Female sex hormones and their modulators - North & East

    Referral Criteria

    Required in referral letter (referrals submitted without this information may be returned):

    1) Treatments in general practice

    i. details of treatments tried or reasons why not appropriate should be recorded in the referral letter

    ii. please specify if there is a clinical reason why a LNG-IUD is not appropriate for the patient

    iii. desire to retain uterus/fertility

    2) Findings of pelvic and speculum examination

    3) BMI

    4) Pelvic (transvaginal if available) ultrasound scan

    5) Up to date smear, as per local guideline (however it is not necessary to perform additional smears as this is not an investigation for bleeding of any kind)

    6) Full Blood Count (FBC)

    To ensure all the required information is attached, a referral proforma is available to download: HMB-Referral-Template-No-Merge-fields

    Please note, the referral proforma is not mandatory.

    Referral Instructions

    For Referral to Gynaecology

    e-Referral Service selection:

    • Specialty: Gynaecology
    • Clinic Type: Menstrual Disorders
    • Service: DRSS-Northern-Gynaecology- Devon ICB - 15N

    Referral Form

    HMB referral template

    Patient Information

    MyHealth patient information - HMB

    Evidence

    NICE guidance - ng88

    Pathway Group

    This guideline has been signed off on behalf of NHS Devon.

    Publication date: November 2018

    Updated: December 24